• Advanced Courses in Life Sciences

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Online Course – 4th Edition

MORPHOLOGICAL PHYLOGENETICS: PRINCIPLES, APPLICATIONS, AND TECHNIQUES

August 16th-27th, 2021

This course will be delivered live online

Online live sessions from Monday 16th to Friday 20th and from Monday 23rd to Friday 27th; from 16:00 to 19:30 (GMT+2, Madrid time zone).

 

Morphological phylogenetics principles applications and techniquesCourse Overview

An accurate reconstruction of evolutionary relationships among species is the cornerstone of evolutionary biology. Building phylogenetic trees thus provides the fundamental framework upon which systematic, biogeographic and evolutionary research operates. Morphological phylogenetics provides a unique toolkit for inferring relationships, considering that the vast majority of the species that have ever lived are now extinct and can only be assessed based on morphological data. Additionally, combining fossils and morphological data with molecular data from extant species is becoming the most comprehensive method of assessing phylogenetic relationships on deep time and the time of origin of major evolutionary lineages. In this course, we will focus on the analysis of morphological data (and combining morphological data with molecular data) using multiple optimality criteria for phylogenetic inference. We will discuss the best available approaches to construct morphological data sets and their impact on phylogenies. We will follow with theory and hands-on practice of phylogenetic programs using maximum parsimony, maximum likelihood and Bayesian inference. Participants will learn how to combine morphological and molecular data for total evidence analyses, how to conduct time-calibrations using tip and node dating, different birth-death models, morphological clocks and combined evidence relaxed clock analyses. Software: MesquiteTNTRAxMLIQTree, Mr. Bayes and BEAST.

REQUIREMENTS

Prior knowledge of concepts in systematics and phylogenetics is strongly recommended. All participants must have a personal computer (Windows, Macintosh). Webcam and headphones are needed for the correct development of the class, as well as a good internet connection.

Contact

courses@transmittingscience.com

Dates

August 16th-27th, 2021

Schedule and Course length

Online live sessions from Monday 16th to Friday 20th and from Monday 23rd to Friday 27th; from 16:00 to 19:30 (GMT+2, Madrid time zone).

35 hours live online.

This course is equivalent to 2 ECTS (European Credit Transfer System) at the Life Science Zurich Graduate School.

The recognition of ECTS by other institutions depends on each university or school.

Language

English

Places

Places are limited to 18 participants and will be occupied by strict registration order.

Participants who have completed the course will receive a certificate at the end of it.

Tiago Simoes instructor for Transmitting Science

Dr. Tiago Simões
Harvard University
United States of America

Oksana Vernygora instructor for Transmitting Science

Oksana Vernygora
University of Alberta
Canada

Haris Saslis coordinator for Transmitting Science

Dr. Haris Saslis
Transmitting Science
Greece

Program

  • Theory of morphological character construction:
      • Homology: assessment and tests.
      • Avoiding logical and biological biases in morphological characters.
      • Challenges behind morphological data sets in the era of big data.
    • Working with data files:
      • File structure of main types of data matrices (NEXUS, PHYLIP, TNT).
      • Creating and editing data files.
    •  Practice:
      • Exercise 1.1: Morphological character construction.
    • Maximum Parsimony:
      • Principles and assumptions.
      • Fitch, Farris, and Goloboff algorithms.
      • Tree search using New Technology (T.N.T) – introduction to the T.N.T. software.
    • Practice: maximum parsimony analysis using T.N.T.:
      • Morphological data analysis using Traditional and New Technology search algorithms.
      • Implied weights parsimony analysis.
      • Working with trees – constructing consensus, calculating support values, mapping synapomorphies, etc.
    • Probabilistic methods in phylogenetics:
      • Concepts and assumptions.
      • Differences between probabilistic methods and parsimony (includes discussion on the performance comparison MP vs ML and BI for morphological data).
    • Maximum likelihood:
      • Theory of maximum likelihood.
      • Application in phylogenetics.
    • Exercise 1: Maximum likelihood analysis in IQ-tree using web-server.
    • Exercise 2: Maximum likelihood analysis using command line version of IQ-tree.
    • Bayesian inference:
      • Bayes theorem and its application in phylogenetics.
      • Introduction to Markov chain Monte Carlo (MCMC) method.
      • Metropolis coupling of MCMC chains.
      • Priors.
    • Introduction to Mr Bayes software.
    • Clock-based (time calibrated) Bayesian inference analysis:
      • Principle behind molecular clock.
      • Introduction to morphological clock.
      • Types of clocks (strict, autocorrelated, uncorrelated, local).
    • Tree priors:
      • Birth-Death model.
      • Fossilized Birth-Death model.
    • Exercise 1: Bayesian inference analysis using Mr Bayes:
      • Writing and adding Mr Bayes block to a data set.
      • Performing non-clock analysis and overview of each component.
      • Analysing output.
    • Exercise 2: Model-fit analysis using Bayes factor.
    • Exercise 3: Time-calibrated analysis in Mr Bayes.
    • Combined data sets:
      • Combining different types of data (molecular and morphological.
      • Divergence time estimation using combined evidence clocks.
      • Analysing output.
    • Clock analysis using BEAST:
      • Major differences to Mr Bayes
      • Overview of the modular configuration of BEAST 2.
    • Exercise 1: Data partitioning and running combined evidence analysis.
    • Exercise 2: Time-calibrated analysis using BEAST 2 (Morphology and combined evidence datasets).

Fees

  • Course Fee
  • Early bird (until June 30th, 2021):
  • 590 € *
    (472 € for Ambassador Institutions)
  • Regular (after June 30th, 2021):
  • 730 € *
    (584 € for Ambassador Institutions)
  • This includes course material (VAT included).
    After registration you will receive confirmation of your acceptance in the course. Payment is not required during registration.

You can check the list of Ambassador Institutions. If you want your institution to become a Transmitting Science Ambassador please contact us at communication@transmittingscience.com

Testimonials for this course

Morphological phylogenetics: principles, applications, and techniques (online) – 2nd edition

“I really like the detailed handouts for some of the sessions. It would be great to have these for all of the sessions. Sometimes the course progressed so quickly it was hard to manipulate a dataset while at the same time to understand the process and change the input files. The instructors were exceptional in their knowledge and up-to-date firsthand knowledge of analyzing morphological data and provided some of the recent papers on the topic which was very good. They were also very open with their knowledge, often times I find that scientists are a bit guarded with giving out detailed information. “Knowledge is power” …. Hats down for an awesome course!!!”

Morphological phylogenetics: principles, applications, and techniques (online) – 2nd edition

“The lectures were well-delivered and course materials were very helpful. The online format certainly seemed to make it more difficult to ensure that everyone was up to speed during the practicals. Perhaps the practicals would be more streamlined with increased use of breakout rooms so that one of the instructors could work with students individually if necessary.”

Funding

Discounts are not cumulative and apply only on the Course Fee. We offer the possibility of paying in two instalments (contact courses@transmittingscience.com).

Former participants will have a 5 % discount on the Course Fee.

20 % discount on the Course Fee is offered for members of some organizations (Ambassador Institutions). If you want to apply to this discount please indicate it in the Registration form (proof will be asked later).

Unemployed scientists living in Spain may benefit from a 40 % discount on the Course Fee. If you would like to enquire about this discount, please contact the course coordinator. That would apply for a maximum of 2 places and they will be covered by strict registration order.

Registration

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